Paroxysmal cold hemoglobinuria: report of a case with an exceptionally high thermal range Donath-Landsteiner antibody.
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چکیده
منابع مشابه
Measurement of Donath - Landsteiner Antibody - producing Cells in Idiopathic Nonsyphilitic Paroxysmal Cold Hemoglobinuria
A 2-yr-old girl with a nonsyphilitic type of and DL titer was 1 : 1 6. Thereafter the PFC paroxysmal cold hemoglobinuria (PCH) decreased in number as the DL titer deis reported. We applied the plaque-formcreased. Eight weeks later circulating PFC ing cell (PFC) assay to the measurement of were not found but the DL titer was still Donath-Landsteiner (DL) antibody-produc1 : 1 positive. The PFC as...
متن کاملCase report: paroxysmal cold hemoglobinuria presenting during pregnancy
BACKGROUND Paroxysmal cold hemoglobinuria is caused by a biphasic IgG autoantibody that triggers complement-mediated intravascular hemolysis. Paroxysmal cold hemoglobinuria has not previously been reported to occur in association with pregnancy. CASE PRESENTATION We report a case of an 18 year old female who presented in early pregnancy with acute hemolytic anemia and a positive Donath-Landst...
متن کاملMeasurement of Donath - Landsteiner Antibody - producing Cells in Idiopathic
A 2-yr-old girl with a nonsyphilitic type of and DL titer was 1 : 1 6. Thereafter the PFC paroxysmal cold hemoglobinuria (PCH) decreased in number as the DL titer deis reported. We applied the plaque-formcreased. Eight weeks later circulating PFC ing cell (PFC) assay to the measurement of were not found but the DL titer was still Donath-Landsteiner (DL) antibody-produc1 : 1 positive. The PFC as...
متن کاملMeasurement of Donath-Landsteiner antibody-producing cells in idiopathic nonsyphilitic paroxysmal cold hemoglobinuria (PCH) in children.
A 2-yr-old girl with a nonsyphilitic type of paroxysmal cold hemoglobinuria (PCH) is reported. We applied the plaque-forming cell (PFC) assay to the measurement of Donath-Landsteiner (DL) antibody-producing cells in the patient. Some of the circulating B lymphocytes formed plaques in our assay system. Initially the number of PFC was 1442 +/- 225/10(6) lymphocytes and DL titer was 1:16. Thereaf...
متن کاملParoxysmal cold haemoglobinuria and measles.
With the increasing control of congenital syphilis, paroxysmal cold haemoglobinuria has become a very rare disorder in childhood. Cases which occur now are more likely to be associated with acute infectious diseases (Kissmeyer-Nielsen and Schleisner, 1963). However, despite the frequency of measles in children, paroxysmal cold haemoglobinuria (PCH) has only previously been described as a compli...
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ورودعنوان ژورنال:
- Blood
دوره 38 4 شماره
صفحات -
تاریخ انتشار 1971